Sunday 9, July | Monday 10, July | Tuesday 11, July | Wednesday 12, July | Thursday 13, July


Wednesday 12, July
09.00 10.30  IS3: Biostatistics for High Dimensional Data  OC31: Design and analysis of clinical trials 4  OC32: Multistate survival analysis and dynamic prediction 2  OC33: Heterogeneity in biomedical studies and meta-analysis  OC34: Statistical challenges of EHR (eHealth Records) analysis  PC6: Topic TBA
10.30 11.00 Coffee break     
11.00 12.00 Keynote Speaker: Francesca Dominici, Harvard University, USA
Model Uncertainty and Covariate Selection in Causal Inference      
12.00 13.00 ISCB Annual General Meeting   ISCB Annual General Meeting
13.00 13.30 Lunch break
13.30 14.30 Lunch break
14.30 16.00  IS1: Bayesian Methods in Clinical Research  OC35: Complex survival data 2  OC36: Statistical methods for precision
medicine 2

 OC37: Design and analysis of clinical

trials 5

 OC38: Statistical methods in

epidemiology 3

 PC7: Topic TBA
16.00 16.30 Coffee break     
16.30 18.00  IS4: Clinical Trial Simulations: the When, Where and What  OC39: Bayesian methods in clinical research 5  OC40: Joint modelling in practice 3

 OC41: Topics in biostatstics 2


 OC42: Survival

analysis 4

 PC8: Topic TBA
18.00 18.30  ISCB39 Presentation     
20.00   Conference Dinner at Hotel Pazo Los Escudos (Beach of Alcabre)






 IS3: Biostatistics for High Dimensional Data


Organised by Jeanine Houwing-Dustermaat, University of Leeds, United Kingdom

    Room: TBA


IS3-1 Pietro Lio, University of Cambridge, United Kingdom - An Integrative Network-Based Analysis of Multi-Omics for Survival Cancer Data

IS3-2 Hae Won Uh, Leiden University Medical Center, The Netherlands - Latent Variable Modelling for Multiple Omics Data

IS3-3 John Whittaker, Glaxo Smith Kline Pharmaceuticals, United Kingdom - Genomics and Drug Discovery 



 OC31: Design and analysis of clinical trials 4

    OC31-1 (09.00-09.18) Corine Baayen - Sequential trials in the context of competing risks – a case study
    OC31-2 (09.19-09.36) Kevin Kunzmann - Test-compatible inference for adaptive two-stage single-arm designs with binary endpoint
    OC31-3 (09.37-09.54) Meinhard Kieser - Optimal planning of phase II/III programs for clinical trials with multiple endpoints
    OC31-4 (09.55-10.12) Ayon Mukherjee - Covariate-adjusted response-adaptive designs in clinical trials where the survival responses of patients follow a semi-parametric model
    OC31-5 (10.12-10.30) Matteo Quartagno - A new design for trials for finding optimal treatment duration

 OC32: Multistate survival analysis and dynamic prediction 2

    OC32-1 (09.00-09.18) Krithika Suresh [StCA winner] - Comparison of joint modeling and landmarking for dynamic prediction under an illness-death model
    OC32-2 (09.19-09.36) Ulrich Beyer - Predicting treatment outcome using intermediate state information based on a multistate landmark model including pre-landmark co-variables
    OC32-3 (09.37-09.54) Maja Katharina Von Cube - A dynamic prediction approach to analyse the population-attributable fraction of ventilator associated pneumonia
    OC32-4 (09.55-10.12) Leyla Azarang - Multi-state net survival model
    OC32-5 (10.12-10.30) Brice Ozenne - Assessing treatment effects on registry data in presence of competing risks

 OC33: Heterogeneity in biomedical studies and meta-analysis 

    OC33-1 (09.00-09.18) Danielle Burke - Guidance for deriving and presenting percentage study weights in meta-analysis of test accuracy studies
    OC33-2 (09.19-09.36) Samprit Banerjee - A semi-parametric approach for meta-analysis of survival curves from orthopedic registries
    OC33-3 (09.37-09.54) David Phillippo - Population-adjusted treatment comparisons: estimates based on Matching-Adjusted Indirect Comparison and Simulated Treatment Comparison
    OC33-4 (09.55-10.12) Fotios Siannis - Longitudinal meta-analysis of percentile ratios for survival data
    OC33-5 (10.12-10.30) Valentijn De Jong - Individual patient data meta-analysis of time-to-event data: A review of the methodology

 OC34: Statistical challenges of EHR (eHealth Records) analysis 

    OC34-1 (09.00-09.18) Clemence Leyrat - How should missing time-varying confounders be handled to estimate marginal effects from electronic health records?
    OC34-2 (09.19-09.36) Olympia Papachristofi - The role of Electronic Health Records in the design of trials of complex interventions: a view from surgery
    OC34-3 (09.37-09.54) Lauren Rodgers - A quasi-experimental approach to account for unmeasured confounders in the assessment of side effects using observational data
    OC34-4 (09.55-10.12) Kristi Krebs - Genetic variation in the Estonian population: a pharmacogenomic study of adverse drug reactions using electronic health records
    OC34-5 (10.12-10.30) David Cheng [StCA winner] - Efficient and robust semi-supervised estimation of treatment effects in electronic medical records data

 PC6: Topic TBA


 Coffee break


 Keynote Speaker: Francesca Dominici, Harvard University, USA

    Model Uncertainty and Covariate Selection in Causal Inference

 ISCB Annual General Meeting


Lunch break


IS1: Bayesian Methods in Clinical Research

    Organised by Carmen Armero, University of Valencia, Spain
    Room: TBA


IS1-1 Heinz Schmidli, Novartis Pharma AG, Switzerland - Bayesian Evidence Synthesis for Extrapolation in Clinical Research

IS1-2 Peter Müller, University of Texas at Austin, USA - A Population-Finding Design with Covariate-Dependent Random Partitions 

IS1-3 Lisa Hampson, Lancaster University, United Kingdom - Use of Bayesian Approaches for Extrapolating from Adult Efficacy Data to Design and Interpret Confirmatory Trials in Children



 OC35: Complex survival data 2

    OC35-1 (14.30-14.48) Ruth Keogh - Flexible modelling of personalised dynamic prediction curves using landmarking, with a case-study in cystic fibrosis
    OC35-2 (14.49-15.06) Kaspar Rufibach - Joint modelling of progression-free and overall survival
    OC35-3 (15.07-15.24) Mailis Amico - A ROC curve approach for cure status prediction from survival data
    OC35-4 (15.25-15.42) Anna Wolski - Comparison of net survival with non-proportional hazard functions: a test based on restricted net survival time
    OC35-5 (15.43-16.00) Song Yang - Improving the testing of treatment effect in clinical trials with time to event outcomes

 OC36: Statistical methods for precision medicine 2

    OC36-1 (14.30-14.48) Kukatharmini Tharmaratnam - Point and interval estimation for predicting individual treatment effect based on randomized clinical trial data
    OC36-2 (14.49-15.06) Zhi Zhao - Approaches to incorporate drug-drug similarity in multi-response penalized likelihood methods for predicting drug response based on multi-omics data
    OC36-3 (15.07-15.24) Erik Van Werkhoven - Development of treatment-selection markers for studies with failure-time outcomes
    OC36-4 (15.25-15.42) Antonia Marsden - Evaluating treatment effect modification on the additive scale to investigate predictors of differential treatment response
    OC36-5 (15.43-16.00) Taesung Park - Pathway-based approach to NGS data with multiple phenotypes

 OC37: Design and analysis of clinical trials 5

    OC37-1 (14.30-14.48) Yida Chiu - Graphical displays for subgroup analysis in clinical trials
    OC37-2 (14.49-15.06) Lieven Desmet - A correlation test for central statistical monitoring of multicenter clinical trials
    OC37-3 (15.07-15.24) Frank Bretz - Assessing the similarity of dose response and target doses in two non-overlapping populations
    OC37-4 (15.25-15.42) Jordam Elm - Use of ordinal scale endpoint in therapeutic influenza clinical study
    OC37-5 (15.43-16.00) Zoe Moodie - Correlates of risk and protection of CYD-TDV, the first licensed dengue vaccine in endemic countries

 OC38: Statistical methods in epidemiology 3

    OC38-1 (14.30-14.48) Evangelia Christodoulou - Using indices to estimate the association of >1 exposures with quantitative, binary and time-to event health outcomes 
    OC38-2 (14.49-15.06) Coraline Danieli - Modeling of cumulative effects of time-varying drug exposures on changes in a longitudinal biomarker
    OC38-3 (15.07-15.24) Helene Jacqmin-Gadda - Weighted two-stage calibration for adjustment on unobserved confounders with non-representative validation sample

OC38-4 (15.25-15.42) David Van Klaveren - The calibrated model-based concordance improved assessment of discriminative ability in patient clusters of limited sample size

    OC38-5 (15.43-16.00) Pedro Sa-Couto - A graphical guideline for the selection of reliability and agreement methods for clinical studies

 PC7: Topic TBA


Coffee break


 IS4: Clinical Trial Simulations: the When, Where and What

    Organised by Geraldine Rauch, University of Heidelberg, Germany
    Room: TBA


IS4-1 Frank Konietschke, University of Dallas, USA - Parametric and Nonparametric Bootstrap Methods for General MANOVA

IS4-2 Tim Friede, Georg-August University of Göttingen, Germany (Co-author: Norbert Benda, BfArM, Bonn) - A Framework for Simulations in Clinical Research with Applications in Small Populations and Rare Diseases

IS4-3 Antje Jahn, University of Mainz, Germany - Simulating Recurrent Event Data with a Calendar Time Scale


 OC39: Bayesian methods in clinical research 5

    OC39-1 (16.30-16.48) Pablo Emilio Verde - The hierarchical meta-regression approach and learning from clinical evidence
    OC39-2 (16.49-17.06) Miguel Caubet Fernández - A Bayesian multivariate latent t-model for assessing the effects of intracranial radiotherapy and corticosteroid therapy on cardiometabolic risk factors in survivors of childhood acute lymphoblastic leukemia
    OC39-3 (17.07-17.24) Despina Vasileiou - Bayesian clinical trial design for rare diseases; prior opinion elicitation for Chronic Rheumatoid Multifocal Osteomyelitis
    OC39-4 (17.25-17.42) Christian Röver - Extrapolation in meta-analysis
    OC39-5 (17.43-18.00) Elena Lázaro - Dealing with baseline hazard functions in Bayesian joint models

 OC40: Joint modelling in practice 3

    OC40-1 (16.30-16.48) Anaïs Rouanet - Dynamic predictions from joint models for multiple longitudinal markers correlated to interval-censored competing events
    OC40-2 (16.49-17.06) Sara Baart - Joint models for longitudinal and time-to-event data in a case-cohort design
    OC40-3 (17.07-17.24) Sam Brilleman [StCA winner] - Bayesian joint models for multiple longitudinal biomarkers and a time-to-event outcome: software development and a melanoma case study
    OC40-4 (17.25-17.42) Maria Sudell - Practical methods to pool multi-study joint longitudinal and time to event data
    OC40-5 (17.43-18.00) Roger Marshall - Enhancing regression  nomograms  to provide a graphical representation of disease risk prediction regression models

 OC41: Topics in biostatistics 2

    OC41-1 (16.30-16.48) Robin Ristl - Simultaneous inference for multiple marginal GEE models with small sample sizes
    OC41-2 (16.49-17.06) Sabine Hoffmann - Elicitation of the knowledge of several experts to derive informative prior distributions on biological parameters in radiation epidemiology
    OC41-3 (17.07-17.24) Javier Rivera - Getting relevant groups of bacteria in microbiome analysis
    OC41-4 (17.25-17.42) María Álvarez Hernández - Alfa coefficient: an alternative measure of categorical agreement among many raters
    OC41-5 (17.43-18.00) Abhik Ghosh [CASc winner] - Robust inference under the beta regression model with application to health care studies

 OC42: Survival analysis 4

    OC42-1 (16.30-16.48) Adina Najwa Kamarudin - Measuring the effectiveness of diagnostic markers in the presence of measurement error through the use of time-dependent ROC curve methodology
    OC42-2 (16.49-17.06) Steve Su - Flexible parametric accelerated failure model
    OC42-3 (17.07-17.24) Enya Weber - Comparison of approaches to joint modelling of progression-free survival and overall survival in cancer trials
    OC42-4 (17.25-17.42) Michel Hof - A probabilistic record linkage model for left truncated time-to-event data with competing risks
    OC42-5 (17.43-18.00) Menglan Pang - Flexible accelerated failure time model for right censored data in survival analysis

 PC8: Topic TBA


 ISCB39 Presentation


 Conference Dinner at Hotel Pazo Los Escudos (Beach of Alcabre)


Location: Pazo Los Escudos, Avda. Atlántida, 106


Map >>

    • [StCA winner]

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